Meta-analysis identifies seven susceptibility loci involved in the atopic march
Identifieur interne : 002B45 ( Main/Exploration ); précédent : 002B44; suivant : 002B46Meta-analysis identifies seven susceptibility loci involved in the atopic march
Auteurs : Ingo Marenholz [Allemagne] ; Jorge Esparza-Gordillo [Allemagne] ; Franz Rüschendorf [Allemagne] ; Anja Bauerfeind [Allemagne] ; David P. Strachan [Royaume-Uni] ; Ben D. Spycher [Suisse] ; Hansjörg Baurecht [Allemagne] ; Patricia Margaritte-Jeannin [France] ; Annika S F [Suède] ; Marjan Kerkhof [Pays-Bas] ; Markus Ege [Allemagne] ; Svetlana Baltic [Australie] ; Melanie C. Matheson [Australie] ; Jin Li [États-Unis] ; Sven Michel [Allemagne] ; Wei Q. Ang [Australie] ; Wendy Mcardle [Royaume-Uni] ; Andreas Arnold [Allemagne] ; Georg Homuth [Allemagne] ; Florence Demenais [France] ; Emmanuelle Bouzigon [France] ; Cilla Söderh Ll [Suède] ; Göran Pershagen [Suède] ; Johan C. De Jongste [Pays-Bas] ; Dirkje S. Postma [Pays-Bas] ; Charlotte Braun-Fahrl Nder [Suisse] ; Elisabeth Horak [Autriche] ; Ludmila M. Ogorodova [Russie] ; Valery P. Puzyrev [Russie] ; Elena Yu Bragina [Russie] ; Thomas J. Hudson [Canada] ; Charles Morin [Canada] ; David L. Duffy [Australie] ; Guy B. Marks [Australie] ; Colin F. Robertson [Australie] ; Grant W. Montgomery [Australie] ; Bill Musk [Australie] ; Philip J. Thompson [Australie] ; Nicholas G. Martin [Australie] ; Alan James [Australie] ; Patrick Sleiman [États-Unis] ; Elina Toskala [États-Unis] ; Elke Rodriguez [Allemagne] ; Regina Fölster-Holst [Allemagne] ; Andre Franke [Allemagne] ; Wolfgang Lieb [Allemagne] ; Christian Gieger [Allemagne] ; Andrea Heinzmann [Allemagne] ; Ernst Rietschel [Allemagne] ; Thomas Keil [Allemagne] ; Sven Cichon [Allemagne, Suisse] ; Markus M. Nöthen [Allemagne] ; Craig E. Pennell [Australie] ; Peter D. Sly [Australie] ; Carsten O. Schmidt [Allemagne] ; Anja Matanovic [Allemagne] ; Valentin Schneider [Allemagne] ; Matthias Heinig [Allemagne] ; Norbert Hübner [Allemagne] ; Patrick G. Holt [Australie] ; Susanne Lau [Allemagne] ; Michael Kabesch [Allemagne] ; Stefan Weidinger [Allemagne] ; Hakon Hakonarson [États-Unis] ; Manuel A. R. Ferreira [Australie] ; Catherine Laprise [Canada] ; Maxim B. Freidin [Russie] ; Jon Genuneit [Allemagne] ; Gerard H. Koppelman [Pays-Bas] ; Erik Melén [Suède] ; Marie- Hélène Dizier [France] ; A John Henderson [Royaume-Uni] ; Young Ae Lee [Allemagne]Source :
- Nature Communications [ 2041-1723 ] ; 2015.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Asthme (génétique), Eczéma atopique (génétique), Enfant, Enfant d'âge préscolaire, Facteur de transcription Ikaros (génétique), Facteurs de transcription (génétique), Femelle, Génotype, Humains, Interleukine-4 (génétique), Jeune adulte, Kinésine (génétique), Modèles logistiques, Mâle, Phénotype, Polymorphisme de nucléotide simple, Protéines adaptatrices du transport vésiculaire (génétique), Protéines de liaison au calcium (génétique), Protéines de liaison à l'ADN (génétique), Protéines de répression (génétique), Protéines de tissu nerveux (génétique), Protéines de transport (génétique), Protéines membranaires (génétique), Protéines nucléaires (génétique), Protéines tumorales (génétique), Prédisposition génétique à une maladie, Récepteur FGFR1 (génétique), Systèmes de transport d'acides aminés neutres (génétique), Étude d'association pangénomique, Évolution de la maladie.
- MESH :
- génétique : Asthme, Eczéma atopique, Facteur de transcription Ikaros, Facteurs de transcription, Interleukine-4, Kinésine, Protéines adaptatrices du transport vésiculaire, Protéines de liaison au calcium, Protéines de liaison à l'ADN, Protéines de répression, Protéines de tissu nerveux, Protéines de transport, Protéines membranaires, Protéines nucléaires, Protéines tumorales, Récepteur FGFR1, Systèmes de transport d'acides aminés neutres.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Génotype, Humains, Jeune adulte, Modèles logistiques, Mâle, Phénotype, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Étude d'association pangénomique, Évolution de la maladie.
English descriptors
- KwdEn :
- Adaptor Proteins, Vesicular Transport (genetics), Adolescent, Adult, Amino Acid Transport Systems, Neutral (genetics), Asthma (genetics), Calcium-Binding Proteins (genetics), Carrier Proteins (genetics), Child, Child, Preschool, DNA-Binding Proteins (genetics), Dermatitis, Atopic (genetics), Disease Progression, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Humans, Ikaros Transcription Factor (genetics), Interleukin-4 (genetics), Kinesin (genetics), Logistic Models, Male, Membrane Proteins (genetics), Middle Aged, Neoplasm Proteins (genetics), Nerve Tissue Proteins (genetics), Nuclear Proteins (genetics), Phenotype, Polymorphism, Single Nucleotide, Receptor, Fibroblast Growth Factor, Type 1 (genetics), Repressor Proteins (genetics), Transcription Factors (genetics), Young Adult.
- MESH :
- chemical , genetics : Adaptor Proteins, Vesicular Transport, Amino Acid Transport Systems, Neutral, Calcium-Binding Proteins, Carrier Proteins, DNA-Binding Proteins, Ikaros Transcription Factor, Interleukin-4, Kinesin, Membrane Proteins, Neoplasm Proteins, Nerve Tissue Proteins, Nuclear Proteins, Receptor, Fibroblast Growth Factor, Type 1, Repressor Proteins, Transcription Factors.
- genetics : Asthma, Dermatitis, Atopic.
- Adolescent, Adult, Child, Child, Preschool, Disease Progression, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Humans, Logistic Models, Male, Middle Aged, Phenotype, Polymorphism, Single Nucleotide, Young Adult.
Abstract
Eczema often precedes the development of asthma in a disease course called the ‘atopic march'. To unravel the genes underlying this characteristic pattern of allergic disease, we conduct a multi-stage genome-wide association study on infantile eczema followed by childhood asthma in 12 populations including 2,428 cases and 17,034 controls. Here we report two novel loci specific for the combined eczema plus asthma phenotype, which are associated with allergic disease for the first time; rs9357733 located in
Url:
DOI: 10.1038/ncomms9804
PubMed: 26542096
PubMed Central: 4667629
Affiliations:
- Allemagne, Australie, Autriche, Canada, France, Pays-Bas, Royaume-Uni, Russie, Suisse, Suède, États-Unis
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Le document en format XML
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Ang</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>School of Women and Infant's Health, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mcardle, Wendy" sort="Mcardle, Wendy" uniqKey="Mcardle W" first="Wendy" last="Mcardle">Wendy Mcardle</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>School of Social and Community Medicine, University of Bristol</institution>, Bristol,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Arnold, Andreas" sort="Arnold, Andreas" uniqKey="Arnold A" first="Andreas" last="Arnold">Andreas Arnold</name><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Clinic and Polyclinic of Dermatology, University Medicine Greifswald</institution>, Greifswald,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt-University Greifswald</institution>, Greifswald,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Demenais, Florence" sort="Demenais, Florence" uniqKey="Demenais F" first="Florence" last="Demenais">Florence Demenais</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bouzigon, Emmanuelle" sort="Bouzigon, Emmanuelle" uniqKey="Bouzigon E" first="Emmanuelle" last="Bouzigon">Emmanuelle Bouzigon</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Soderh Ll, Cilla" sort="Soderh Ll, Cilla" uniqKey="Soderh Ll C" first="Cilla" last="Söderh Ll">Cilla Söderh Ll</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Department of Biosciences and Nutrition, and Center for Innovative Medicine (CIMED), Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Pershagen, Goran" sort="Pershagen, Goran" uniqKey="Pershagen G" first="Göran" last="Pershagen">Göran Pershagen</name><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Institute of Environmental Medicine, Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Jongste, Johan C" sort="De Jongste, Johan C" uniqKey="De Jongste J" first="Johan C." last="De Jongste">Johan C. De Jongste</name><affiliation wicri:level="1"><nlm:aff id="a20"><institution>Department of Pediatrics, Pediatric Chest Center, Erasmus University Medical Center</institution>, Rotterdam,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S." last="Postma">Dirkje S. Postma</name><affiliation wicri:level="1"><nlm:aff id="a21"><institution>Department of Pulmonology and GRIAC Research Institute, University of Groningen, University Medical Center Groningen</institution>, Groningen,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Braun Fahrl Nder, Charlotte" sort="Braun Fahrl Nder, Charlotte" uniqKey="Braun Fahrl Nder C" first="Charlotte" last="Braun-Fahrl Nder">Charlotte Braun-Fahrl Nder</name><affiliation wicri:level="1"><nlm:aff id="a22"><institution>Swiss Tropical and Public Health Institute and the University of Basel</institution>, Basel,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Horak, Elisabeth" sort="Horak, Elisabeth" uniqKey="Horak E" first="Elisabeth" last="Horak">Elisabeth Horak</name><affiliation wicri:level="1"><nlm:aff id="a23"><institution>Division of Pediatric Cardiology and Pulmonology, Department of Pediatrics, Innsbruck Medical University</institution>, Innsbruck,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ogorodova, Ludmila M" sort="Ogorodova, Ludmila M" uniqKey="Ogorodova L" first="Ludmila M." last="Ogorodova">Ludmila M. Ogorodova</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Siberian State Medical University</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Puzyrev, Valery P" sort="Puzyrev, Valery P" uniqKey="Puzyrev V" first="Valery P." last="Puzyrev">Valery P. Puzyrev</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Siberian State Medical University</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Research Institute of Medical Genetics</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bragina, Elena Yu" sort="Bragina, Elena Yu" uniqKey="Bragina E" first="Elena Yu" last="Bragina">Elena Yu Bragina</name><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Research Institute of Medical Genetics</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hudson, Thomas J" sort="Hudson, Thomas J" uniqKey="Hudson T" first="Thomas J." last="Hudson">Thomas J. Hudson</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Ontario Institute for Cancer Research</institution>, Toronto, Ontario,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Morin, Charles" sort="Morin, Charles" uniqKey="Morin C" first="Charles" last="Morin">Charles Morin</name><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Centre de santé et de services sociaux de Chicoutimi</institution>, Saguenay, Québec,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Duffy, David L" sort="Duffy, David L" uniqKey="Duffy D" first="David L." last="Duffy">David L. Duffy</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Marks, Guy B" sort="Marks, Guy B" uniqKey="Marks G" first="Guy B." last="Marks">Guy B. Marks</name><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Woolcock Institute of Medical Research, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Robertson, Colin F" sort="Robertson, Colin F" uniqKey="Robertson C" first="Colin F." last="Robertson">Colin F. Robertson</name><affiliation wicri:level="1"><nlm:aff id="a30"><institution>Department of Respiratory Medicine, Murdoch Children's Research Institute</institution>, Melbourne, Victoria,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><affiliation wicri:level="1"><nlm:aff id="a31"><institution>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Thompson, Philip J" sort="Thompson, Philip J" uniqKey="Thompson P" first="Philip J." last="Thompson">Philip J. Thompson</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Lung Institute of Western Australia, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><affiliation wicri:level="1"><nlm:aff id="a31"><institution>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sleiman, Patrick" sort="Sleiman, Patrick" uniqKey="Sleiman P" first="Patrick" last="Sleiman">Patrick Sleiman</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Center for Applied Genomics, The Children's Hospital of Philadelphia</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Toskala, Elina" sort="Toskala, Elina" uniqKey="Toskala E" first="Elina" last="Toskala">Elina Toskala</name><affiliation wicri:level="1"><nlm:aff id="a33"><institution>Department of Otolaryngology—Head and Neck Surgery, Temple University, School of Medicine</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rodriguez, Elke" sort="Rodriguez, Elke" uniqKey="Rodriguez E" first="Elke" last="Rodriguez">Elke Rodriguez</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Folster Holst, Regina" sort="Folster Holst, Regina" uniqKey="Folster Holst R" first="Regina" last="Fölster-Holst">Regina Fölster-Holst</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><affiliation wicri:level="1"><nlm:aff id="a34"><institution>Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lieb, Wolfgang" sort="Lieb, Wolfgang" uniqKey="Lieb W" first="Wolfgang" last="Lieb">Wolfgang Lieb</name><affiliation wicri:level="1"><nlm:aff id="a35"><institution>Institute of Epidemiology, Christian-Albrechts-University of Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="a36"><institution>Research Unit of Molecular Epidemiology and Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health</institution>, Neuherberg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heinzmann, Andrea" sort="Heinzmann, Andrea" uniqKey="Heinzmann A" first="Andrea" last="Heinzmann">Andrea Heinzmann</name><affiliation wicri:level="1"><nlm:aff id="a37"><institution>University Children's Hospital, Albert Ludwigs University</institution>, Freiburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rietschel, Ernst" sort="Rietschel, Ernst" uniqKey="Rietschel E" first="Ernst" last="Rietschel">Ernst Rietschel</name><affiliation wicri:level="1"><nlm:aff id="a38"><institution>University Children's Hospital, University of Cologne</institution>, Cologne,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Keil, Thomas" sort="Keil, Thomas" uniqKey="Keil T" first="Thomas" last="Keil">Thomas Keil</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Institute of Social Medicine, Epidemiology and Health Economics, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a40"><institution>Institute for Clinical Epidemiology and Biometry, University of Würzburg</institution>, Würzburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><affiliation wicri:level="1"><nlm:aff id="a41"><institution>Institute of Human Genetics, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a42"><institution>Department of Genomics, Life & Brain Center, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a43"><institution>Division of Medical Genetics, University Hospital Basel and Department of Biomedicine, University of Basel</institution>, Basel,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a44"><institution>Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organisation of the Brain, Genomic Imaging, Research Centre Jülich</institution>, Jülich,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M." last="Nöthen">Markus M. Nöthen</name><affiliation wicri:level="1"><nlm:aff id="a41"><institution>Institute of Human Genetics, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a42"><institution>Department of Genomics, Life & Brain Center, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E." last="Pennell">Craig E. Pennell</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>School of Women and Infant's Health, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sly, Peter D" sort="Sly, Peter D" uniqKey="Sly P" first="Peter D." last="Sly">Peter D. Sly</name><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Queensland Children's Medical Research Institute, University of Queensland</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Carsten O" sort="Schmidt, Carsten O" uniqKey="Schmidt C" first="Carsten O." last="Schmidt">Carsten O. Schmidt</name><affiliation wicri:level="1"><nlm:aff id="a46"><institution>Institute for Community Medicine, Study of Health in Pomerania/KEF, University Medicine Greifswald</institution>, Greifswald,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Matanovic, Anja" sort="Matanovic, Anja" uniqKey="Matanovic A" first="Anja" last="Matanovic">Anja Matanovic</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Schneider, Valentin" sort="Schneider, Valentin" uniqKey="Schneider V" first="Valentin" last="Schneider">Valentin Schneider</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heinig, Matthias" sort="Heinig, Matthias" uniqKey="Heinig M" first="Matthias" last="Heinig">Matthias Heinig</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a47"><institution>Max Planck Institute for Molecular Genetics</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hubner, Norbert" sort="Hubner, Norbert" uniqKey="Hubner N" first="Norbert" last="Hübner">Norbert Hübner</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Holt, Patrick G" sort="Holt, Patrick G" uniqKey="Holt P" first="Patrick G." last="Holt">Patrick G. Holt</name><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Queensland Children's Medical Research Institute, University of Queensland</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a48"><institution>Telethon Kids Institute, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lau, Susanne" sort="Lau, Susanne" uniqKey="Lau S" first="Susanne" last="Lau">Susanne Lau</name><affiliation wicri:level="1"><nlm:aff id="a49"><institution>Department of Pediatric Pneumology and Immunology, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kabesch, Michael" sort="Kabesch, Michael" uniqKey="Kabesch M" first="Michael" last="Kabesch">Michael Kabesch</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Pediatric Pneumology and Allergy, University Childreǹs Hospital Regensburg (KUNO)</institution>, Regensburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Weidinger, Stefan" sort="Weidinger, Stefan" uniqKey="Weidinger S" first="Stefan" last="Weidinger">Stefan Weidinger</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Center for Applied Genomics, The Children's Hospital of Philadelphia</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ferreira, Manuel A R" sort="Ferreira, Manuel A R" uniqKey="Ferreira M" first="Manuel A. R." last="Ferreira">Manuel A. R. Ferreira</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Laprise, Catherine" sort="Laprise, Catherine" uniqKey="Laprise C" first="Catherine" last="Laprise">Catherine Laprise</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Université du Québec à Chicoutimi</institution>, Saguenay, Québec,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Freidin, Maxim B" sort="Freidin, Maxim B" uniqKey="Freidin M" first="Maxim B." last="Freidin">Maxim B. Freidin</name><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Research Institute of Medical Genetics</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Genuneit, Jon" sort="Genuneit, Jon" uniqKey="Genuneit J" first="Jon" last="Genuneit">Jon Genuneit</name><affiliation wicri:level="1"><nlm:aff id="a51"><institution>Institute of Epidemiology and Medical Biometry, Ulm University</institution>, Ulm,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Koppelman, Gerard H" sort="Koppelman, Gerard H" uniqKey="Koppelman G" first="Gerard H." last="Koppelman">Gerard H. Koppelman</name><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Department of Pediatric Pulmonology and Pediatric Allergology, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital and GRIAC Research Institute</institution>, Groningen,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Melen, Erik" sort="Melen, Erik" uniqKey="Melen E" first="Erik" last="Melén">Erik Melén</name><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Institute of Environmental Medicine, Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a53"><institution>Sachs' Children's Hospital</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dizier, Marie Helene" sort="Dizier, Marie Helene" uniqKey="Dizier M" first="Marie- Hélène" last="Dizier">Marie- Hélène Dizier</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Henderson, A John" sort="Henderson, A John" uniqKey="Henderson A" first="A John" last="Henderson">A John Henderson</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>School of Social and Community Medicine, University of Bristol</institution>, Bristol,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lee, Young Ae" sort="Lee, Young Ae" uniqKey="Lee Y" first="Young Ae" last="Lee">Young Ae Lee</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26542096</idno><idno type="pmc">4667629</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667629</idno><idno type="RBID">PMC:4667629</idno><idno type="doi">10.1038/ncomms9804</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000747</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000747</idno><idno type="wicri:Area/Pmc/Curation">000746</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000746</idno><idno type="wicri:Area/Pmc/Checkpoint">000E65</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000E65</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002758</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002758</idno><idno type="wicri:Area/PubMed/Curation">002689</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002689</idno><idno type="wicri:Area/PubMed/Checkpoint">002689</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002689</idno><idno type="wicri:Area/Ncbi/Merge">002D25</idno><idno type="wicri:Area/Ncbi/Curation">002D25</idno><idno type="wicri:Area/Ncbi/Checkpoint">002D25</idno><idno type="wicri:Area/Main/Merge">002B45</idno><idno type="wicri:Area/Main/Curation">002B45</idno><idno type="wicri:Area/Main/Exploration">002B45</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Meta-analysis identifies seven susceptibility loci involved in the atopic march</title><author><name sortKey="Marenholz, Ingo" sort="Marenholz, Ingo" uniqKey="Marenholz I" first="Ingo" last="Marenholz">Ingo Marenholz</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Esparza Gordillo, Jorge" sort="Esparza Gordillo, Jorge" uniqKey="Esparza Gordillo J" first="Jorge" last="Esparza-Gordillo">Jorge Esparza-Gordillo</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ruschendorf, Franz" sort="Ruschendorf, Franz" uniqKey="Ruschendorf F" first="Franz" last="Rüschendorf">Franz Rüschendorf</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bauerfeind, Anja" sort="Bauerfeind, Anja" uniqKey="Bauerfeind A" first="Anja" last="Bauerfeind">Anja Bauerfeind</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Population Health Research Institute, St George's, University of London</institution>, London,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Spycher, Ben D" sort="Spycher, Ben D" uniqKey="Spycher B" first="Ben D." last="Spycher">Ben D. Spycher</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Institute of Social and Preventive Medicine, University of Bern</institution>, Bern,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Baurecht, Hansjorg" sort="Baurecht, Hansjorg" uniqKey="Baurecht H" first="Hansjörg" last="Baurecht">Hansjörg Baurecht</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Margaritte Jeannin, Patricia" sort="Margaritte Jeannin, Patricia" uniqKey="Margaritte Jeannin P" first="Patricia" last="Margaritte-Jeannin">Patricia Margaritte-Jeannin</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="S F, Annika" sort="S F, Annika" uniqKey="S F A" first="Annika" last="S F">Annika S F</name><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Institute of Environmental Medicine, Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kerkhof, Marjan" sort="Kerkhof, Marjan" uniqKey="Kerkhof M" first="Marjan" last="Kerkhof">Marjan Kerkhof</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>University of Groningen, University Medical Center Groningen, GRIAC Research Institute</institution>, Groningen,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ege, Markus" sort="Ege, Markus" uniqKey="Ege M" first="Markus" last="Ege">Markus Ege</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Dr von Hauner Children's Hospital, Ludwig Maximilians University Munich, Member of the German Center for Lung Research (DZL)</institution>, Munich,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Baltic, Svetlana" sort="Baltic, Svetlana" uniqKey="Baltic S" first="Svetlana" last="Baltic">Svetlana Baltic</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Lung Institute of Western Australia, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Matheson, Melanie C" sort="Matheson, Melanie C" uniqKey="Matheson M" first="Melanie C." last="Matheson">Melanie C. Matheson</name><affiliation wicri:level="1"><nlm:aff id="a12"><institution>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne</institution>, Melbourne, Victoria,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jin" sort="Li, Jin" uniqKey="Li J" first="Jin" last="Li">Jin Li</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Center for Applied Genomics, The Children's Hospital of Philadelphia</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Michel, Sven" sort="Michel, Sven" uniqKey="Michel S" first="Sven" last="Michel">Sven Michel</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Pediatric Pneumology and Allergy, University Childreǹs Hospital Regensburg (KUNO)</institution>, Regensburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ang, Wei Q" sort="Ang, Wei Q" uniqKey="Ang W" first="Wei Q." last="Ang">Wei Q. Ang</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>School of Women and Infant's Health, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mcardle, Wendy" sort="Mcardle, Wendy" uniqKey="Mcardle W" first="Wendy" last="Mcardle">Wendy Mcardle</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>School of Social and Community Medicine, University of Bristol</institution>, Bristol,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Arnold, Andreas" sort="Arnold, Andreas" uniqKey="Arnold A" first="Andreas" last="Arnold">Andreas Arnold</name><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Clinic and Polyclinic of Dermatology, University Medicine Greifswald</institution>, Greifswald,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt-University Greifswald</institution>, Greifswald,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Demenais, Florence" sort="Demenais, Florence" uniqKey="Demenais F" first="Florence" last="Demenais">Florence Demenais</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bouzigon, Emmanuelle" sort="Bouzigon, Emmanuelle" uniqKey="Bouzigon E" first="Emmanuelle" last="Bouzigon">Emmanuelle Bouzigon</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Soderh Ll, Cilla" sort="Soderh Ll, Cilla" uniqKey="Soderh Ll C" first="Cilla" last="Söderh Ll">Cilla Söderh Ll</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Department of Biosciences and Nutrition, and Center for Innovative Medicine (CIMED), Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Pershagen, Goran" sort="Pershagen, Goran" uniqKey="Pershagen G" first="Göran" last="Pershagen">Göran Pershagen</name><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Institute of Environmental Medicine, Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Jongste, Johan C" sort="De Jongste, Johan C" uniqKey="De Jongste J" first="Johan C." last="De Jongste">Johan C. De Jongste</name><affiliation wicri:level="1"><nlm:aff id="a20"><institution>Department of Pediatrics, Pediatric Chest Center, Erasmus University Medical Center</institution>, Rotterdam,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S." last="Postma">Dirkje S. Postma</name><affiliation wicri:level="1"><nlm:aff id="a21"><institution>Department of Pulmonology and GRIAC Research Institute, University of Groningen, University Medical Center Groningen</institution>, Groningen,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Braun Fahrl Nder, Charlotte" sort="Braun Fahrl Nder, Charlotte" uniqKey="Braun Fahrl Nder C" first="Charlotte" last="Braun-Fahrl Nder">Charlotte Braun-Fahrl Nder</name><affiliation wicri:level="1"><nlm:aff id="a22"><institution>Swiss Tropical and Public Health Institute and the University of Basel</institution>, Basel,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Horak, Elisabeth" sort="Horak, Elisabeth" uniqKey="Horak E" first="Elisabeth" last="Horak">Elisabeth Horak</name><affiliation wicri:level="1"><nlm:aff id="a23"><institution>Division of Pediatric Cardiology and Pulmonology, Department of Pediatrics, Innsbruck Medical University</institution>, Innsbruck,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ogorodova, Ludmila M" sort="Ogorodova, Ludmila M" uniqKey="Ogorodova L" first="Ludmila M." last="Ogorodova">Ludmila M. Ogorodova</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Siberian State Medical University</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Puzyrev, Valery P" sort="Puzyrev, Valery P" uniqKey="Puzyrev V" first="Valery P." last="Puzyrev">Valery P. Puzyrev</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Siberian State Medical University</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Research Institute of Medical Genetics</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bragina, Elena Yu" sort="Bragina, Elena Yu" uniqKey="Bragina E" first="Elena Yu" last="Bragina">Elena Yu Bragina</name><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Research Institute of Medical Genetics</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hudson, Thomas J" sort="Hudson, Thomas J" uniqKey="Hudson T" first="Thomas J." last="Hudson">Thomas J. Hudson</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Ontario Institute for Cancer Research</institution>, Toronto, Ontario,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Morin, Charles" sort="Morin, Charles" uniqKey="Morin C" first="Charles" last="Morin">Charles Morin</name><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Centre de santé et de services sociaux de Chicoutimi</institution>, Saguenay, Québec,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Duffy, David L" sort="Duffy, David L" uniqKey="Duffy D" first="David L." last="Duffy">David L. Duffy</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Marks, Guy B" sort="Marks, Guy B" uniqKey="Marks G" first="Guy B." last="Marks">Guy B. Marks</name><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Woolcock Institute of Medical Research, University of Sydney</institution>, Sydney, New South Wales,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Robertson, Colin F" sort="Robertson, Colin F" uniqKey="Robertson C" first="Colin F." last="Robertson">Colin F. Robertson</name><affiliation wicri:level="1"><nlm:aff id="a30"><institution>Department of Respiratory Medicine, Murdoch Children's Research Institute</institution>, Melbourne, Victoria,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><affiliation wicri:level="1"><nlm:aff id="a31"><institution>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Thompson, Philip J" sort="Thompson, Philip J" uniqKey="Thompson P" first="Philip J." last="Thompson">Philip J. Thompson</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Lung Institute of Western Australia, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><affiliation wicri:level="1"><nlm:aff id="a31"><institution>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sleiman, Patrick" sort="Sleiman, Patrick" uniqKey="Sleiman P" first="Patrick" last="Sleiman">Patrick Sleiman</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Center for Applied Genomics, The Children's Hospital of Philadelphia</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Toskala, Elina" sort="Toskala, Elina" uniqKey="Toskala E" first="Elina" last="Toskala">Elina Toskala</name><affiliation wicri:level="1"><nlm:aff id="a33"><institution>Department of Otolaryngology—Head and Neck Surgery, Temple University, School of Medicine</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rodriguez, Elke" sort="Rodriguez, Elke" uniqKey="Rodriguez E" first="Elke" last="Rodriguez">Elke Rodriguez</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Folster Holst, Regina" sort="Folster Holst, Regina" uniqKey="Folster Holst R" first="Regina" last="Fölster-Holst">Regina Fölster-Holst</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><affiliation wicri:level="1"><nlm:aff id="a34"><institution>Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lieb, Wolfgang" sort="Lieb, Wolfgang" uniqKey="Lieb W" first="Wolfgang" last="Lieb">Wolfgang Lieb</name><affiliation wicri:level="1"><nlm:aff id="a35"><institution>Institute of Epidemiology, Christian-Albrechts-University of Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="a36"><institution>Research Unit of Molecular Epidemiology and Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health</institution>, Neuherberg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heinzmann, Andrea" sort="Heinzmann, Andrea" uniqKey="Heinzmann A" first="Andrea" last="Heinzmann">Andrea Heinzmann</name><affiliation wicri:level="1"><nlm:aff id="a37"><institution>University Children's Hospital, Albert Ludwigs University</institution>, Freiburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rietschel, Ernst" sort="Rietschel, Ernst" uniqKey="Rietschel E" first="Ernst" last="Rietschel">Ernst Rietschel</name><affiliation wicri:level="1"><nlm:aff id="a38"><institution>University Children's Hospital, University of Cologne</institution>, Cologne,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Keil, Thomas" sort="Keil, Thomas" uniqKey="Keil T" first="Thomas" last="Keil">Thomas Keil</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Institute of Social Medicine, Epidemiology and Health Economics, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a40"><institution>Institute for Clinical Epidemiology and Biometry, University of Würzburg</institution>, Würzburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><affiliation wicri:level="1"><nlm:aff id="a41"><institution>Institute of Human Genetics, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a42"><institution>Department of Genomics, Life & Brain Center, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a43"><institution>Division of Medical Genetics, University Hospital Basel and Department of Biomedicine, University of Basel</institution>, Basel,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a44"><institution>Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organisation of the Brain, Genomic Imaging, Research Centre Jülich</institution>, Jülich,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M." last="Nöthen">Markus M. Nöthen</name><affiliation wicri:level="1"><nlm:aff id="a41"><institution>Institute of Human Genetics, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a42"><institution>Department of Genomics, Life & Brain Center, University of Bonn</institution>, Bonn,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E." last="Pennell">Craig E. Pennell</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>School of Women and Infant's Health, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sly, Peter D" sort="Sly, Peter D" uniqKey="Sly P" first="Peter D." last="Sly">Peter D. Sly</name><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Queensland Children's Medical Research Institute, University of Queensland</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Carsten O" sort="Schmidt, Carsten O" uniqKey="Schmidt C" first="Carsten O." last="Schmidt">Carsten O. Schmidt</name><affiliation wicri:level="1"><nlm:aff id="a46"><institution>Institute for Community Medicine, Study of Health in Pomerania/KEF, University Medicine Greifswald</institution>, Greifswald,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Matanovic, Anja" sort="Matanovic, Anja" uniqKey="Matanovic A" first="Anja" last="Matanovic">Anja Matanovic</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Schneider, Valentin" sort="Schneider, Valentin" uniqKey="Schneider V" first="Valentin" last="Schneider">Valentin Schneider</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heinig, Matthias" sort="Heinig, Matthias" uniqKey="Heinig M" first="Matthias" last="Heinig">Matthias Heinig</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a47"><institution>Max Planck Institute for Molecular Genetics</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hubner, Norbert" sort="Hubner, Norbert" uniqKey="Hubner N" first="Norbert" last="Hübner">Norbert Hübner</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Holt, Patrick G" sort="Holt, Patrick G" uniqKey="Holt P" first="Patrick G." last="Holt">Patrick G. Holt</name><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Queensland Children's Medical Research Institute, University of Queensland</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a48"><institution>Telethon Kids Institute, University of Western Australia</institution>, Perth, Western Australia,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lau, Susanne" sort="Lau, Susanne" uniqKey="Lau S" first="Susanne" last="Lau">Susanne Lau</name><affiliation wicri:level="1"><nlm:aff id="a49"><institution>Department of Pediatric Pneumology and Immunology, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kabesch, Michael" sort="Kabesch, Michael" uniqKey="Kabesch M" first="Michael" last="Kabesch">Michael Kabesch</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Pediatric Pneumology and Allergy, University Childreǹs Hospital Regensburg (KUNO)</institution>, Regensburg,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Weidinger, Stefan" sort="Weidinger, Stefan" uniqKey="Weidinger S" first="Stefan" last="Weidinger">Stefan Weidinger</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel</institution>, Kiel,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Center for Applied Genomics, The Children's Hospital of Philadelphia</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania</institution>, Philadelphia, Pennsylvania,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ferreira, Manuel A R" sort="Ferreira, Manuel A R" uniqKey="Ferreira M" first="Manuel A. R." last="Ferreira">Manuel A. R. Ferreira</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>QIMR Berghofer Medical Research Institute</institution>, Brisbane, Queensland,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Laprise, Catherine" sort="Laprise, Catherine" uniqKey="Laprise C" first="Catherine" last="Laprise">Catherine Laprise</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Université du Québec à Chicoutimi</institution>, Saguenay, Québec,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Freidin, Maxim B" sort="Freidin, Maxim B" uniqKey="Freidin M" first="Maxim B." last="Freidin">Maxim B. Freidin</name><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Research Institute of Medical Genetics</institution>, Tomsk,<country>Russia</country></nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Genuneit, Jon" sort="Genuneit, Jon" uniqKey="Genuneit J" first="Jon" last="Genuneit">Jon Genuneit</name><affiliation wicri:level="1"><nlm:aff id="a51"><institution>Institute of Epidemiology and Medical Biometry, Ulm University</institution>, Ulm,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Koppelman, Gerard H" sort="Koppelman, Gerard H" uniqKey="Koppelman G" first="Gerard H." last="Koppelman">Gerard H. Koppelman</name><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Department of Pediatric Pulmonology and Pediatric Allergology, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital and GRIAC Research Institute</institution>, Groningen,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Melen, Erik" sort="Melen, Erik" uniqKey="Melen E" first="Erik" last="Melén">Erik Melén</name><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Institute of Environmental Medicine, Karolinska Institutet</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a53"><institution>Sachs' Children's Hospital</institution>, Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dizier, Marie Helene" sort="Dizier, Marie Helene" uniqKey="Dizier M" first="Marie- Hélène" last="Dizier">Marie- Hélène Dizier</name><affiliation wicri:level="1"><nlm:aff id="a6"><institution>Inserm, UMR-946</institution>, F-75010 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Université Paris Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie</institution>, F-75007 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Henderson, A John" sort="Henderson, A John" uniqKey="Henderson A" first="A John" last="Henderson">A John Henderson</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>School of Social and Community Medicine, University of Bristol</institution>, Bristol,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lee, Young Ae" sort="Lee, Young Ae" uniqKey="Lee Y" first="Young Ae" last="Lee">Young Ae Lee</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Max-Delbrück-Center (MDC) for Molecular Medicine</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité University Medical Center</institution>, Berlin,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Nature Communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adaptor Proteins, Vesicular Transport (genetics)</term><term>Adolescent</term><term>Adult</term><term>Amino Acid Transport Systems, Neutral (genetics)</term><term>Asthma (genetics)</term><term>Calcium-Binding Proteins (genetics)</term><term>Carrier Proteins (genetics)</term><term>Child</term><term>Child, Preschool</term><term>DNA-Binding Proteins (genetics)</term><term>Dermatitis, Atopic (genetics)</term><term>Disease Progression</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Genotype</term><term>Humans</term><term>Ikaros Transcription Factor (genetics)</term><term>Interleukin-4 (genetics)</term><term>Kinesin (genetics)</term><term>Logistic Models</term><term>Male</term><term>Membrane Proteins (genetics)</term><term>Middle Aged</term><term>Neoplasm Proteins (genetics)</term><term>Nerve Tissue Proteins (genetics)</term><term>Nuclear Proteins (genetics)</term><term>Phenotype</term><term>Polymorphism, Single Nucleotide</term><term>Receptor, Fibroblast Growth Factor, Type 1 (genetics)</term><term>Repressor Proteins (genetics)</term><term>Transcription Factors (genetics)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Asthme (génétique)</term><term>Eczéma atopique (génétique)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteur de transcription Ikaros (génétique)</term><term>Facteurs de transcription (génétique)</term><term>Femelle</term><term>Génotype</term><term>Humains</term><term>Interleukine-4 (génétique)</term><term>Jeune adulte</term><term>Kinésine (génétique)</term><term>Modèles logistiques</term><term>Mâle</term><term>Phénotype</term><term>Polymorphisme de nucléotide simple</term><term>Protéines adaptatrices du transport vésiculaire (génétique)</term><term>Protéines de liaison au calcium (génétique)</term><term>Protéines de liaison à l'ADN (génétique)</term><term>Protéines de répression (génétique)</term><term>Protéines de tissu nerveux (génétique)</term><term>Protéines de transport (génétique)</term><term>Protéines membranaires (génétique)</term><term>Protéines nucléaires (génétique)</term><term>Protéines tumorales (génétique)</term><term>Prédisposition génétique à une maladie</term><term>Récepteur FGFR1 (génétique)</term><term>Systèmes de transport d'acides aminés neutres (génétique)</term><term>Étude d'association pangénomique</term><term>Évolution de la maladie</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Adaptor Proteins, Vesicular Transport</term><term>Amino Acid Transport Systems, Neutral</term><term>Calcium-Binding Proteins</term><term>Carrier Proteins</term><term>DNA-Binding Proteins</term><term>Ikaros Transcription Factor</term><term>Interleukin-4</term><term>Kinesin</term><term>Membrane Proteins</term><term>Neoplasm Proteins</term><term>Nerve Tissue Proteins</term><term>Nuclear Proteins</term><term>Receptor, Fibroblast Growth Factor, Type 1</term><term>Repressor Proteins</term><term>Transcription Factors</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Asthma</term><term>Dermatitis, Atopic</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Asthme</term><term>Eczéma atopique</term><term>Facteur de transcription Ikaros</term><term>Facteurs de transcription</term><term>Interleukine-4</term><term>Kinésine</term><term>Protéines adaptatrices du transport vésiculaire</term><term>Protéines de liaison au calcium</term><term>Protéines de liaison à l'ADN</term><term>Protéines de répression</term><term>Protéines de tissu nerveux</term><term>Protéines de transport</term><term>Protéines membranaires</term><term>Protéines nucléaires</term><term>Protéines tumorales</term><term>Récepteur FGFR1</term><term>Systèmes de transport d'acides aminés neutres</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Child</term><term>Child, Preschool</term><term>Disease Progression</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Genotype</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Phenotype</term><term>Polymorphism, Single Nucleotide</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Génotype</term><term>Humains</term><term>Jeune adulte</term><term>Modèles logistiques</term><term>Mâle</term><term>Phénotype</term><term>Polymorphisme de nucléotide simple</term><term>Prédisposition génétique à une maladie</term><term>Étude d'association pangénomique</term><term>Évolution de la maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Eczema often precedes the development of asthma in a disease course called the ‘atopic march'. To unravel the genes underlying this characteristic pattern of allergic disease, we conduct a multi-stage genome-wide association study on infantile eczema followed by childhood asthma in 12 populations including 2,428 cases and 17,034 controls. Here we report two novel loci specific for the combined eczema plus asthma phenotype, which are associated with allergic disease for the first time; rs9357733 located in <italic>EFHC1</italic> on chromosome 6p12.3 (OR 1.27; <italic>P=</italic>2.1 × 10<sup>−8</sup>) and rs993226 between <italic>TMTC2</italic> and <italic>SLC6A15</italic> on chromosome 12q21.3 (OR 1.58; <italic>P=</italic>5.3 × 10<sup>−9</sup>). Additional susceptibility loci identified at genome-wide significance are <italic>FLG</italic> (1q21.3), <italic>IL4/KIF3A</italic> (5q31.1), <italic>AP5B1/OVOL1</italic> (11q13.1), <italic>C11orf30/LRRC32</italic> (11q13.5) and <italic>IKZF3</italic> (17q21). We show that predominantly eczema loci increase the risk for the atopic march. Our findings suggest that eczema may play an important role in the development of asthma after eczema.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dharmage, S C" uniqKey="Dharmage S">S. C. Dharmage</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spergel, J M" uniqKey="Spergel J">J. M. Spergel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almqvist, C" uniqKey="Almqvist C">C. Almqvist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ricci, G" uniqKey="Ricci G">G. Ricci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leung, D Y" uniqKey="Leung D">D. Y. Leung</name></author><author><name sortKey="Guttman Yassky, E" uniqKey="Guttman Yassky E">E. Guttman-Yassky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, M" uniqKey="Li M">M. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kemeny, L" uniqKey="Kemeny L">L. Kemeny</name></author><author><name sortKey="Szabo, K" uniqKey="Szabo K">K. Szabo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Palmer, C N" uniqKey="Palmer C">C. N. Palmer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marenholz, I" uniqKey="Marenholz I">I. Marenholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Punekar, Y S" uniqKey="Punekar Y">Y. S. Punekar</name></author><author><name sortKey="Sheikh, A" uniqKey="Sheikh A">A. Sheikh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freedman, M L" uniqKey="Freedman M">M. L. Freedman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paternoster, L" uniqKey="Paternoster L">L. Paternoster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marenholz, I" uniqKey="Marenholz I">I. Marenholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esparza Gordillo, J" uniqKey="Esparza Gordillo J">J. Esparza-Gordillo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moffatt, M F" uniqKey="Moffatt M">M. F. Moffatt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bisgaard, H" uniqKey="Bisgaard H">H. Bisgaard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Halapi, E" uniqKey="Halapi E">E. Halapi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hinds, D A" uniqKey="Hinds D">D. A. Hinds</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferreira, M A" uniqKey="Ferreira M">M. A. Ferreira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lappalainen, T" uniqKey="Lappalainen T">T. Lappalainen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kundaje, A" uniqKey="Kundaje A">A. Kundaje</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eppig, J T" uniqKey="Eppig J">J. T. Eppig</name></author><author><name sortKey="Blake, J A" uniqKey="Blake J">J. A. Blake</name></author><author><name sortKey="Bult, C J" uniqKey="Bult C">C. J. Bult</name></author><author><name sortKey="Kadin, J A" uniqKey="Kadin J">J. A. Kadin</name></author><author><name sortKey="Richardson, J E" uniqKey="Richardson J">J. E. Richardson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Forrest, A R" uniqKey="Forrest A">A. R. Forrest</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, A D" uniqKey="Johnson A">A. D. Johnson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sunryd, J C" uniqKey="Sunryd J">J. C. Sunryd</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Welter, D" uniqKey="Welter D">D. Welter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Medina, M T" uniqKey="Medina M">M. T. Medina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Annesi, F" uniqKey="Annesi F">F. Annesi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, S" uniqKey="Ma S">S. Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stogmann, E" uniqKey="Stogmann E">E. Stogmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suzuki, T" uniqKey="Suzuki T">T. Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suzuki, T" uniqKey="Suzuki T">T. Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ikeda, T" uniqKey="Ikeda T">T. Ikeda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thomas, B" uniqKey="Thomas B">B. Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silverberg, J I" uniqKey="Silverberg J">J. I. Silverberg</name></author><author><name sortKey="Joks, R" uniqKey="Joks R">R. Joks</name></author><author><name sortKey="Durkin, H G" uniqKey="Durkin H">H. G. Durkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drgonova, J" uniqKey="Drgonova J">J. Drgonova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schuhmacher, A" uniqKey="Schuhmacher A">A. Schuhmacher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kohli, M A" uniqKey="Kohli M">M. A. Kohli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cuboni, S" uniqKey="Cuboni S">S. Cuboni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pasparakis, M" uniqKey="Pasparakis M">M. Pasparakis</name></author><author><name sortKey="Haase, I" uniqKey="Haase I">I. Haase</name></author><author><name sortKey="Nestle, F O" uniqKey="Nestle F">F. O. Nestle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kawasaki, H" uniqKey="Kawasaki H">H. Kawasaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spergel, J M" uniqKey="Spergel J">J. M. Spergel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horimukai, K" uniqKey="Horimukai K">K. Horimukai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simpson, E L" uniqKey="Simpson E">E. L. Simpson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ballardini, N" uniqKey="Ballardini N">N. Ballardini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saunes, M" uniqKey="Saunes M">M. Saunes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Von Kobyletzki, L B" uniqKey="Von Kobyletzki L">L. B. von Kobyletzki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martin, P E" uniqKey="Martin P">P. E. Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Belgrave, D C" uniqKey="Belgrave D">D. C. Belgrave</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noti, M" uniqKey="Noti M">M. Noti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bihouee, T" uniqKey="Bihouee T">T. Bihouee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Longo, G" uniqKey="Longo G">G. Longo</name></author><author><name sortKey="Berti, I" uniqKey="Berti I">I. Berti</name></author><author><name sortKey="Burks, A W" uniqKey="Burks A">A. W. Burks</name></author><author><name sortKey="Krauss, B" uniqKey="Krauss B">B. Krauss</name></author><author><name sortKey="Barbi, E" uniqKey="Barbi E">E. Barbi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chafen, J J" uniqKey="Chafen J">J. J. Chafen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keil, T" uniqKey="Keil T">T. Keil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rona, R J" uniqKey="Rona R">R. J. Rona</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ramasamy, A" uniqKey="Ramasamy A">A. Ramasamy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spergel, J M" uniqKey="Spergel J">J. M. Spergel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kapoor, R" uniqKey="Kapoor R">R. Kapoor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Hulst, A E" uniqKey="Van Der Hulst A">A. E. van der Hulst</name></author><author><name sortKey="Klip, H" uniqKey="Klip H">H. Klip</name></author><author><name sortKey="Brand, P L" uniqKey="Brand P">P. L. Brand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moffatt, M F" uniqKey="Moffatt M">M. F. Moffatt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patterson, N" uniqKey="Patterson N">N. Patterson</name></author><author><name sortKey="Price, A L" uniqKey="Price A">A. L. Price</name></author><author><name sortKey="Reich, D" uniqKey="Reich D">D. Reich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Willer, C J" uniqKey="Willer C">C. J. Willer</name></author><author><name sortKey="Ding, J" uniqKey="Ding J">J. Ding</name></author><author><name sortKey="Scheet, P" uniqKey="Scheet P">P. Scheet</name></author><author><name sortKey="Abecasis, G R" uniqKey="Abecasis G">G. R. Abecasis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Howie, B N" uniqKey="Howie B">B. N. Howie</name></author><author><name sortKey="Donnelly, P" uniqKey="Donnelly P">P. Donnelly</name></author><author><name sortKey="Marchini, J" uniqKey="Marchini J">J. Marchini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Williams, R L" uniqKey="Williams R">R. L. Williams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Willer, C J" uniqKey="Willer C">C. J. Willer</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Abecasis, G R" uniqKey="Abecasis G">G. R. Abecasis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Henderson, J" uniqKey="Henderson J">J. Henderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ballardini, N" uniqKey="Ballardini N">N. Ballardini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schuttelaar, M L" uniqKey="Schuttelaar M">M. L. Schuttelaar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sandilands, A" uniqKey="Sandilands A">A. Sandilands</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Canada</li><li>France</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Russie</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Marenholz, Ingo" sort="Marenholz, Ingo" uniqKey="Marenholz I" first="Ingo" last="Marenholz">Ingo Marenholz</name></noRegion><name sortKey="Arnold, Andreas" sort="Arnold, Andreas" uniqKey="Arnold A" first="Andreas" last="Arnold">Andreas Arnold</name><name sortKey="Bauerfeind, Anja" sort="Bauerfeind, Anja" uniqKey="Bauerfeind A" first="Anja" last="Bauerfeind">Anja Bauerfeind</name><name sortKey="Baurecht, Hansjorg" sort="Baurecht, Hansjorg" uniqKey="Baurecht H" first="Hansjörg" last="Baurecht">Hansjörg Baurecht</name><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name><name sortKey="Ege, Markus" sort="Ege, Markus" uniqKey="Ege M" first="Markus" last="Ege">Markus Ege</name><name sortKey="Esparza Gordillo, Jorge" sort="Esparza Gordillo, Jorge" uniqKey="Esparza Gordillo J" first="Jorge" last="Esparza-Gordillo">Jorge Esparza-Gordillo</name><name sortKey="Esparza Gordillo, Jorge" sort="Esparza Gordillo, Jorge" uniqKey="Esparza Gordillo J" first="Jorge" last="Esparza-Gordillo">Jorge Esparza-Gordillo</name><name sortKey="Folster Holst, Regina" sort="Folster Holst, Regina" uniqKey="Folster Holst R" first="Regina" last="Fölster-Holst">Regina Fölster-Holst</name><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><name sortKey="Genuneit, Jon" sort="Genuneit, Jon" uniqKey="Genuneit J" first="Jon" last="Genuneit">Jon Genuneit</name><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><name sortKey="Heinig, Matthias" sort="Heinig, Matthias" uniqKey="Heinig M" first="Matthias" last="Heinig">Matthias Heinig</name><name sortKey="Heinig, Matthias" sort="Heinig, Matthias" uniqKey="Heinig M" first="Matthias" last="Heinig">Matthias Heinig</name><name sortKey="Heinzmann, Andrea" sort="Heinzmann, Andrea" uniqKey="Heinzmann A" first="Andrea" last="Heinzmann">Andrea Heinzmann</name><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><name sortKey="Hubner, Norbert" sort="Hubner, Norbert" uniqKey="Hubner N" first="Norbert" last="Hübner">Norbert Hübner</name><name sortKey="Kabesch, Michael" sort="Kabesch, Michael" uniqKey="Kabesch M" first="Michael" last="Kabesch">Michael Kabesch</name><name sortKey="Keil, Thomas" sort="Keil, Thomas" uniqKey="Keil T" first="Thomas" last="Keil">Thomas Keil</name><name sortKey="Keil, Thomas" sort="Keil, Thomas" uniqKey="Keil T" first="Thomas" last="Keil">Thomas Keil</name><name sortKey="Lau, Susanne" sort="Lau, Susanne" uniqKey="Lau S" first="Susanne" last="Lau">Susanne Lau</name><name sortKey="Lee, Young Ae" sort="Lee, Young Ae" uniqKey="Lee Y" first="Young Ae" last="Lee">Young Ae Lee</name><name sortKey="Lee, Young Ae" sort="Lee, Young Ae" uniqKey="Lee Y" first="Young Ae" last="Lee">Young Ae Lee</name><name sortKey="Lieb, Wolfgang" sort="Lieb, Wolfgang" uniqKey="Lieb W" first="Wolfgang" last="Lieb">Wolfgang Lieb</name><name sortKey="Marenholz, Ingo" sort="Marenholz, Ingo" uniqKey="Marenholz I" first="Ingo" last="Marenholz">Ingo Marenholz</name><name sortKey="Matanovic, Anja" sort="Matanovic, Anja" uniqKey="Matanovic A" first="Anja" last="Matanovic">Anja Matanovic</name><name sortKey="Matanovic, Anja" sort="Matanovic, Anja" uniqKey="Matanovic A" first="Anja" last="Matanovic">Anja Matanovic</name><name sortKey="Michel, Sven" sort="Michel, Sven" uniqKey="Michel S" first="Sven" last="Michel">Sven Michel</name><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M." last="Nöthen">Markus M. Nöthen</name><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M." last="Nöthen">Markus M. Nöthen</name><name sortKey="Rietschel, Ernst" sort="Rietschel, Ernst" uniqKey="Rietschel E" first="Ernst" last="Rietschel">Ernst Rietschel</name><name sortKey="Rodriguez, Elke" sort="Rodriguez, Elke" uniqKey="Rodriguez E" first="Elke" last="Rodriguez">Elke Rodriguez</name><name sortKey="Ruschendorf, Franz" sort="Ruschendorf, Franz" uniqKey="Ruschendorf F" first="Franz" last="Rüschendorf">Franz Rüschendorf</name><name sortKey="Schmidt, Carsten O" sort="Schmidt, Carsten O" uniqKey="Schmidt C" first="Carsten O." last="Schmidt">Carsten O. Schmidt</name><name sortKey="Schneider, Valentin" sort="Schneider, Valentin" uniqKey="Schneider V" first="Valentin" last="Schneider">Valentin Schneider</name><name sortKey="Weidinger, Stefan" sort="Weidinger, Stefan" uniqKey="Weidinger S" first="Stefan" last="Weidinger">Stefan Weidinger</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P." last="Strachan">David P. Strachan</name></noRegion><name sortKey="Henderson, A John" sort="Henderson, A John" uniqKey="Henderson A" first="A John" last="Henderson">A John Henderson</name><name sortKey="Mcardle, Wendy" sort="Mcardle, Wendy" uniqKey="Mcardle W" first="Wendy" last="Mcardle">Wendy Mcardle</name></country><country name="Suisse"><noRegion><name sortKey="Spycher, Ben D" sort="Spycher, Ben D" uniqKey="Spycher B" first="Ben D." last="Spycher">Ben D. Spycher</name></noRegion><name sortKey="Braun Fahrl Nder, Charlotte" sort="Braun Fahrl Nder, Charlotte" uniqKey="Braun Fahrl Nder C" first="Charlotte" last="Braun-Fahrl Nder">Charlotte Braun-Fahrl Nder</name><name sortKey="Cichon, Sven" sort="Cichon, Sven" uniqKey="Cichon S" first="Sven" last="Cichon">Sven Cichon</name></country><country name="France"><noRegion><name sortKey="Margaritte Jeannin, Patricia" sort="Margaritte Jeannin, Patricia" uniqKey="Margaritte Jeannin P" first="Patricia" last="Margaritte-Jeannin">Patricia Margaritte-Jeannin</name></noRegion><name sortKey="Bouzigon, Emmanuelle" sort="Bouzigon, Emmanuelle" uniqKey="Bouzigon E" first="Emmanuelle" last="Bouzigon">Emmanuelle Bouzigon</name><name sortKey="Bouzigon, Emmanuelle" sort="Bouzigon, Emmanuelle" uniqKey="Bouzigon E" first="Emmanuelle" last="Bouzigon">Emmanuelle Bouzigon</name><name sortKey="Demenais, Florence" sort="Demenais, Florence" uniqKey="Demenais F" first="Florence" last="Demenais">Florence Demenais</name><name sortKey="Demenais, Florence" sort="Demenais, Florence" uniqKey="Demenais F" first="Florence" last="Demenais">Florence Demenais</name><name sortKey="Dizier, Marie Helene" sort="Dizier, Marie Helene" uniqKey="Dizier M" first="Marie- Hélène" last="Dizier">Marie- Hélène Dizier</name><name sortKey="Dizier, Marie Helene" sort="Dizier, Marie Helene" uniqKey="Dizier M" first="Marie- Hélène" last="Dizier">Marie- Hélène Dizier</name><name sortKey="Margaritte Jeannin, Patricia" sort="Margaritte Jeannin, Patricia" uniqKey="Margaritte Jeannin P" first="Patricia" last="Margaritte-Jeannin">Patricia Margaritte-Jeannin</name></country><country name="Suède"><noRegion><name sortKey="S F, Annika" sort="S F, Annika" uniqKey="S F A" first="Annika" last="S F">Annika S F</name></noRegion><name sortKey="Melen, Erik" sort="Melen, Erik" uniqKey="Melen E" first="Erik" last="Melén">Erik Melén</name><name sortKey="Melen, Erik" sort="Melen, Erik" uniqKey="Melen E" first="Erik" last="Melén">Erik Melén</name><name sortKey="Pershagen, Goran" sort="Pershagen, Goran" uniqKey="Pershagen G" first="Göran" last="Pershagen">Göran Pershagen</name><name sortKey="Soderh Ll, Cilla" sort="Soderh Ll, Cilla" uniqKey="Soderh Ll C" first="Cilla" last="Söderh Ll">Cilla Söderh Ll</name></country><country name="Pays-Bas"><noRegion><name sortKey="Kerkhof, Marjan" sort="Kerkhof, Marjan" uniqKey="Kerkhof M" first="Marjan" last="Kerkhof">Marjan Kerkhof</name></noRegion><name sortKey="De Jongste, Johan C" sort="De Jongste, Johan C" uniqKey="De Jongste J" first="Johan C." last="De Jongste">Johan C. De Jongste</name><name sortKey="Koppelman, Gerard H" sort="Koppelman, Gerard H" uniqKey="Koppelman G" first="Gerard H." last="Koppelman">Gerard H. Koppelman</name><name sortKey="Postma, Dirkje S" sort="Postma, Dirkje S" uniqKey="Postma D" first="Dirkje S." last="Postma">Dirkje S. Postma</name></country><country name="Australie"><noRegion><name sortKey="Baltic, Svetlana" sort="Baltic, Svetlana" uniqKey="Baltic S" first="Svetlana" last="Baltic">Svetlana Baltic</name></noRegion><name sortKey="Ang, Wei Q" sort="Ang, Wei Q" uniqKey="Ang W" first="Wei Q." last="Ang">Wei Q. Ang</name><name sortKey="Duffy, David L" sort="Duffy, David L" uniqKey="Duffy D" first="David L." last="Duffy">David L. Duffy</name><name sortKey="Ferreira, Manuel A R" sort="Ferreira, Manuel A R" uniqKey="Ferreira M" first="Manuel A. R." last="Ferreira">Manuel A. R. Ferreira</name><name sortKey="Holt, Patrick G" sort="Holt, Patrick G" uniqKey="Holt P" first="Patrick G." last="Holt">Patrick G. Holt</name><name sortKey="Holt, Patrick G" sort="Holt, Patrick G" uniqKey="Holt P" first="Patrick G." last="Holt">Patrick G. Holt</name><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><name sortKey="Marks, Guy B" sort="Marks, Guy B" uniqKey="Marks G" first="Guy B." last="Marks">Guy B. Marks</name><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><name sortKey="Matheson, Melanie C" sort="Matheson, Melanie C" uniqKey="Matheson M" first="Melanie C." last="Matheson">Melanie C. Matheson</name><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E." last="Pennell">Craig E. Pennell</name><name sortKey="Robertson, Colin F" sort="Robertson, Colin F" uniqKey="Robertson C" first="Colin F." last="Robertson">Colin F. Robertson</name><name sortKey="Sly, Peter D" sort="Sly, Peter D" uniqKey="Sly P" first="Peter D." last="Sly">Peter D. Sly</name><name sortKey="Thompson, Philip J" sort="Thompson, Philip J" uniqKey="Thompson P" first="Philip J." last="Thompson">Philip J. Thompson</name></country><country name="États-Unis"><noRegion><name sortKey="Li, Jin" sort="Li, Jin" uniqKey="Li J" first="Jin" last="Li">Jin Li</name></noRegion><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><name sortKey="Sleiman, Patrick" sort="Sleiman, Patrick" uniqKey="Sleiman P" first="Patrick" last="Sleiman">Patrick Sleiman</name><name sortKey="Sleiman, Patrick" sort="Sleiman, Patrick" uniqKey="Sleiman P" first="Patrick" last="Sleiman">Patrick Sleiman</name><name sortKey="Toskala, Elina" sort="Toskala, Elina" uniqKey="Toskala E" first="Elina" last="Toskala">Elina Toskala</name></country><country name="Autriche"><noRegion><name sortKey="Horak, Elisabeth" sort="Horak, Elisabeth" uniqKey="Horak E" first="Elisabeth" last="Horak">Elisabeth Horak</name></noRegion></country><country name="Russie"><noRegion><name sortKey="Ogorodova, Ludmila M" sort="Ogorodova, Ludmila M" uniqKey="Ogorodova L" first="Ludmila M." last="Ogorodova">Ludmila M. Ogorodova</name></noRegion><name sortKey="Bragina, Elena Yu" sort="Bragina, Elena Yu" uniqKey="Bragina E" first="Elena Yu" last="Bragina">Elena Yu Bragina</name><name sortKey="Freidin, Maxim B" sort="Freidin, Maxim B" uniqKey="Freidin M" first="Maxim B." last="Freidin">Maxim B. Freidin</name><name sortKey="Puzyrev, Valery P" sort="Puzyrev, Valery P" uniqKey="Puzyrev V" first="Valery P." last="Puzyrev">Valery P. Puzyrev</name><name sortKey="Puzyrev, Valery P" sort="Puzyrev, Valery P" uniqKey="Puzyrev V" first="Valery P." last="Puzyrev">Valery P. Puzyrev</name></country><country name="Canada"><noRegion><name sortKey="Hudson, Thomas J" sort="Hudson, Thomas J" uniqKey="Hudson T" first="Thomas J." last="Hudson">Thomas J. Hudson</name></noRegion><name sortKey="Laprise, Catherine" sort="Laprise, Catherine" uniqKey="Laprise C" first="Catherine" last="Laprise">Catherine Laprise</name><name sortKey="Morin, Charles" sort="Morin, Charles" uniqKey="Morin C" first="Charles" last="Morin">Charles Morin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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